منابع مشابه
Substrate-dependent dissociation of malate thiokinase.
Malate thiokinase has been purified to apparent homogeneity by employing conventional purification techniques along with affinity chromatography. The enzyme is composed of two nonidentical subunits (alpha subunit Mr=34,000, beta subunit Mr=42,500) to yield an alpha 4 beta 4 structure for the native enzyme. Phosphorylation of the enzyme by ATP occurs exclusively on the alpha subunit. The phospho...
متن کاملSuccinic Thiokinase. I. Purification of the Enzyme from Pig Heart.
Succinic thiokinase was found by Kaufman et al. (2, 3) and by Hift et al. (4) to be responsible for the substrate level phosphorylation reaction accompanying the oxidation of ar-ketoglutarate. The enzyme has been variously termed phosphorylation (“P”) enzyme (3, 4), GDP phosphorylation enzyme (5), succinic thiokinase (6-S), succinyl-CoA synthetase (9, lo), and succinate:CoA ligase (GDP) (11). T...
متن کاملThe Succinate - Glycine Cycle
This aminoketonic acid is the source of all the carbon atoms of protoporphyrin (2-4). In this series of reactions, t.he a-carbon atom of glycine becomes the b-carbon atom of S-aminolevulinic acid. Since the a-carbon atom of glycine, detached from its carboxyl group, is not only utilized for porphyrin synthesis but also conforms to the metabolic pattern of the “Cl” compounds (3), this carbon acy...
متن کاملCyclooctanaminium hydrogen succinate monohydrate
In the title hydrated salt, C(8)H(18)N(+)·C(4)H(5)O(4) (-)·H(2)O, the cyclo-octyl- ring of the cation is disordered over two positions in a 0.833 (3):0.167 (3) ratio. The structure contains various O-H.·O and N-H⋯O inter-actions, forming a hydrogen-bonded layer of mol-ecules perpendicular to the c axis. In each layer, the ammonium cation hydrogen bonds to two hydrogen succinate anions and one w...
متن کاملAminoguanidinium hydrogen succinate
The title compound, CH(7)N(4) (+)·C(4)H(5)O(4) (-), is a molecular salt containing discrete amino-guanidinium and succinate ions. The amino-guanidinium cation is nearly planar, with a maximum deviation of 0.035 (1) Å. The dihedral angle between the amino-guanidinium cation and the succinate anion is 3.35 (6)°. The crystal packing exhibits inter-molecular N-H⋯O and O-H⋯·O hydrogen bonds.
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1973
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)44439-6